The next gm(48) will take place on Oct 20, 2018. Opening a video file is a different operation on different OSs. This is a reasonable decision by YoYo Games to keep the GMS2 codebase clean and move all platform-dependent, OS-specific source code outside and consider it an extension. here's a bit of logging I do every frame: // Frame X:313 DX:4. This read only variable returns the position (along the x-axis) within the room of the left hand bounding box for the instance, where the bounding box is defined by the maximum width and height of the mask for the instance (as set by the spriteindex or by the maskindex ). Somehow, bboxleft uses a float value as a reference point, despite my x being set as an integer value in my code. The gm(48) is a casual, fun game jam that helps you to learn and grow as a developer. GameMaker Studio 2 moves a lot of built-in functionality from previous versions into extensions. I'm hunting bugs in my projects, and I struggling with some rounding issues and the bboxleft variable. ![]() Shining a light on high-quality projects and resources created by our community.įor more than 8 years, the tight-knit community of /r/gamemaker has run the game jam gm(48) for GameMaker developers of all ages and experience levels. Share the latest pictures and videos of your gameĪre you in need of motivation? Then take a stab at these creative challenges. Scheduled content ScheduleĪsk questions, ask for assistance or ask about something else entirely.ĭiscuss game design and game development. Join in the conversation, get help with any issues you might have and connect with your fellow developers! We also have a Steam Group for playing games. r/gamemaker sponsors three chat-rooms: IRC, a Discord server, and a Slack team. Im hunting bugs in my projects, and I struggling with some rounding issues and the bboxleft variable. Content must be appropriately flaired at the time of submission GameMaker BboxLeft & Negative X Speed Hello.Technical support requests are to be directed to YoYo Games Support. ![]()
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![]() In case you missed the original Hollow Knight game, it is available on Xbox One for $14.99. Check out the video below from Team Cherry to get some more information about this new game! A true testament to the passion and hard work that indie developers like Team Cherry put into their games: a small DLC can turn into a full game. Because this second playable character morphed into an entire sequel, Team Cherry is rewarding their backers with a free code for Silksong on Windows, Mac or Switch. Those who backed their Kickstarter campaign back in 2014 might recall that there was a stretch goal for a second playable character to be included. Her controls in Silksong will be similar to those of the original Hollow Knight game, but Hornet’s repertoire of attacks is new and her movements are more fluid and light. Hornet appears several times in Hollow Knight as a character to advance the story and as a boss fight. ![]() Hollow Knight: Silksong takes place in a new kingdom with a familiar character, Hornet. The team is hopeful to include both Xbox and PS4 versions but cannot, at this time, confirm whether they will be available at the launch. It does not have a set release date yet, but has been announced to be available at launch on Windows, Mac and the Nintendo Switch. The score echoes the majesty and sadness of a civilisation brought to ruin.Team Cherry, the developer behind the popular game, Hollow Knight, announced on February 14th that the long-planned DLC that would add the character, Hornet, to the game as playable has instead been developed as a full-blown, stand-alone game. A haunting, intimate score accompanies the player on their journey, composed by Christopher Larkin.Evolve with powerful new skills and abilities! Gain spells, strength and speed.Track down every last twisted foe and add them to your Hunter’s Journal! Over 130 enemies! 30 epic bosses! Face ferocious beasts and vanquish ancient knights on your quest through the kingdom.Dodge, dash and slash your way through even the most deadly adversaries. ![]() If you like classic gameplay, cute but creepy characters, epic adventure and beautiful, gothic worlds, then Hollow Knight awaits! Features of Hollow Knight The Grimm Troupe: Take in the sights and uncover new wonders hidden off of the beaten path. Every new area you’ll discover is beautifully unique and strange, teeming with new creatures and characters. Explore twisting caverns, ancient cities and deadly wastes battle tainted creatures and befriend bizarre bugs and solve ancient mysteries at the kingdom’s heart.Īn Evocative Hand-Crafted World The world of Hollow Knight is brought to life in vivid, moody detail, its caverns alive with bizarre and terrifying creatures, each animated by hand in a traditional 2D style. Hollow Knight is a classically styled 2D action adventure across a vast interconnected world. Many are drawn below the surface, searching for riches, or glory, or answers to old secrets. New Music. Brave the Depths of a Forgotten Kingdom Beneath the fading town of Dirtmouth sleeps an ancient, ruined kingdom. New Friends. Hidden Dreams – Mighty new foes emerge! New Boss fights. The Grimm Troupe – Light the Nightmare Lantern. You can now fight more enemy creatures in new environments with new abilities. This new DLC got released for Halloween event. Hollow Knight The Grimm Troupe PC Game 2017 Overview: Hollow Knight The Grimm Troupe is an Action, Adventure and Platformer game for PC published by Team Cherry in 2017. ![]() After the download is complete run the installer.A basic set of installation instruction can be found below, but if you are having trouble be sure to check the MiKTeX page (click the previous install hyperlink): The MiKTeX/about page contains several links including how to install, deploy, and update MiKTeX. You will find more information about these frontend programs in the " LaTeX Interfaces" box below.įor a Windows computer it is strongly recommend that you use the common MiKTeX editor. Often these front end programs include help menus, wizards for creating LaTeX objects, drop down menus for inserting symbols or altering text, and many other features that will support both new and experienced LaTeX users. Text editor programs such as TeXwork, TexStudio, TexMaker, and TexShop provide a friendly interface for users. A text editor is a frontend software that can be used to create. Instruction on how to install the most common LaTeX programs for Windows and Mac can be found in the " Installation for Windows" and " Installation for Mac OS X" sections below.Īside from the back end software required to run LaTeX it is highly recommend that users install a text editor. The LaTeX Project provides information about how to install LaTeX on Windows, Macs, and Linux, as well as online services. There are a few different programs available to do this depending on the operating system of the user. ![]() The core of LaTeX is a backend software package that complies the LaTeX code (.tex file) and creates the final document (PDF). ![]() Ariel, Mississippi was third at 974 strikes per square mile. Greensburg, Louisiana came in second at just over 1,000 lightning strikes per square mile. ![]() At a glance you can see how close lightning and decide if you should stay outdoors or be safer inside. Nationally, the community known as Four Corners, Florida - situated about two miles west of Disney's Animal Kingdom resort near the Disney World resort area - had the greatest lightning density of any neighborhood, registering over 1,200 lightning strikes per square mile! With Lightning Tracker app you will know about lightning strikes around you. Vaisala also compiled which city was the "lightning capital" of each state for 2022. Oregon and Washington essentially tied for the next two lowest spots at 2.5 lightning strikes every square mile. LIGHTNING SAFETY: WHEN THUNDER ROARS, EVEN TAKING OUT THE TRASH CAN TURN DEADLYįrigid Alaska averaged only 0.18 lightning strikes per square mile – or put the other way, one lightning strike every 5.5 square miles in 2022. Unlike the warm waters of the Gulf of Mexico and Atlantic Ocean that fuel thunderstorms much of the year, the Pacific Ocean is considerably cooler along the West Coast, tempering the large difference in temperatures needed to trigger thunderstorms. On the other hand, the Pacific Coastal states took up the bottom spots, only interrupted by Maine at No. But it's a big drop from 2021 when the state was hit with 41 million strikes. Texas once again was the state with the most lightning strikes recorded at just under 27.7 million strikes - a consistent top ranking due to its size and prime geographic location for frequent and severe thunderstorms. In the U.S., nearly 200 million lightning strikes (198.2 million) were detected by Vaisala, the highest count since 2019 and a jump from around 194 million last year.Ģ021 LIGHTNING REPORT: US STRUCK BY 194 MILLION BOLTS OF LIGHTNING Texas is no Tonga, but it gets a lot of lightning too During Tonga's volcanic eruption, sensors detected 400,000 lightning strikes over a six-hour period including more than 25,500 lightning strikes in just 5 minutes.ĭuring the peak of the eruption, half of all global lightning was concentrated around the volcano's crater, becoming the greatest concentration of lightning strikes ever recorded, according to Vaisala. Yet it was only a precursor to the Earth-shaking event that would occur the next day when a cataclysmic eruption sent shock waves and a tsunami around the world. TONGA VOLCANIC ERUPTION TRIGGERED 50-FOOT TSUNAMI WAVES, AT LEAST 3 DEAD (NASA Earth Observatory image by Joshua Stevens using GOES imagery courtesy of NOAA and NESDIS) ![]() Crescent-shaped bow shock waves and numerous lightning strikes are also visible. The GOES-17 satellite captured images of an umbrella cloud generated by the underwater eruption of the Hunga Tonga-Hunga Ha’apai volcano on Jan. ![]() Those are not free though.īoy, been having an impossible time doing a simple thing and it just won't work. If you must cut exactly try then Tmpgenc Smart Renderer, SolveigMM Video Splitter or Videoredo. You can't cut exactly because you can only cut at keyframes and those can be several seconds a part. Install MKVtoolnix and then start MKVmerge GUI (or the mmg.exe in the mkvtoolnix folder). Hit Start muxing to extract the new mkv file.Ĭheck the new file inte output destination(by default same folder as your input file). Or if you want to just remove one a single part at the middle of the video then type in 00:00:00-00:45:00,00:47:00-01:50:00 Type in the part you want to extract like 00:21:00-00:22:00 Under Splitting and Split mode choose split by parts based on timecodes Install MKVtoolnix and then start MKVToolnix-GUI.Īdd your mkv video file(you can also add most other video files but it might not work to cut/mux all formats). New MKVtoolnixGUI Guide: (scroll down for old MKVMergeGUI/MMG GUIDE) Just use a video player like MPC-HC and note the cut points you want. It has NO video preview so you must type in the cut points manually. Improved handling of SSA/ASS subtitles.Using the free MKVtoolnix can you cut out parts from a mkv including all audio and subtitle tracks.New registration system tied to the name of the original user account (admin or standard user) which will allow MKVtools to be registered on multiple and upgraded computers (as long as the computers share original account names).This application will NO LONGER create MP4 or AVI videos, use MP4tools or AVItools for that functionality.MKVtools can now be put in a watch mode, where it will monitor a "watch folder" and process any videos added to the folder using the presets.Added user definable "presets" to automate conversion settings, including the option for letting MKVtools "guess" at the best settings.Added user definable "presets" to automate which tracks are selected.The Quick Tab has been removed to be replaced by.Added the ability to create MKV videos from multiple video formats.Initial release of the re-branded version of MKVtools which incorporates all MKV related features of the original version and. ![]() Please help bring the beta software into general release by sending feedback to: - 1/27/12 (changes from MKVtools 2.4.7) If MKVtools doesn't quite do what you want it to, you can see if there is a beta version of the software found here. Remember you can find your registration code in the preference panel of the current version. If you are updating from a pre-3.5.x version, the preferences have been updated and as a result you will need to re-enter your presets, registration code and other preferences. It has been tested on a MacBook Pro and a Mac Pro with no known issues. MKVtools is Intel-only (64-bit) and requires Mac OS X 10.9.x or later. ![]() If you decide to register, download the software using the link below, and then follow these registration instructions. This will get you a registration code that unlocks all of the suite apps. When registering, you have the option of registering for just MKVtools, or you can choose to register for the VIDEOtoolbox suite of applications for less than the cost of registering two applications. You should probably consider this software as being sold "as is", so test thoroughly to see if you think you’re getting your moneys worth before registering. Bugs still exist which may or may not get fixed and there are known issues and probably some unknown issues :-). ![]() Note, that the output of the registered and unregistered versions of MKVtools will be identical, so you can thoroughly test MKVtools before you decide to support it’s development. Hopefully you will consider the usefulness of this software to be worth the price of a meal at McDonald's :-). The above limitations will disappear if you register the software ($5.99 - the price of a Big Mac dinner around here).
![]() Have you trouble falling asleep? This app helps you to sleep well by blocking the external noises. – No audible loop thanks to redesigned audio engine – No streaming is required for playback (no data connection required) – Ability to use the app along with other apps – Individual volume adjustment for rain, thunders and music – 6 thunder and 6 music mixable with the rain sounds – 45+ perfectly looped rain sounds (free and HD) Relax your mind, remove the stress and find your inner peace. The rain sounds and relaxing music have beneficial effects on the body and soothing the mind because, by covering the external environment noise, promote relaxation and help in different occasions: for better sleep, to concentrate in work, study or reading, for meditation, etc. At the end of the set time, the sound fades gently and the app closes by itself, so you do not have to worry about close it if you fall asleep. It is also possible to set a timer and turn off the screen. You can keep the app in the background in conjunction with other apps (for listening your favorite music, play games or browse the internet). You can adjust the volume of rain, thunder and music individually to find the ideal combination and so encourage a deep relaxation of the mind. Ideal for sleeping, power nap, meditation, concentration or if you have tinnitus problems (ringing in the ears). Over 50 rain sounds (free and HD) mixable with thunders and music in order to reach a state of complete relaxation. The largest collection of relaxing rain for Android. Premium Unlocked : If you’ve ever tried to use a Premium feature on Relax Rain mod download and found that it was blocked or not available Most apps restrict access to premium features only to those who have paid for them. More Features: With no ads comes more choice – you can use this app with unlocked features unlocked.Įnhanced App experience: Since there are no interruptions between scenes thanks to ad removal, using Relax Rain APK MOD feels much smoother and faster than using the regular Relax Rain MOD APK v6.3.1. This means that you can use this app without ever being interrupted by annoying commercials. No ads: Unlike the standard version of the Relax Rain apk, which features intrusive advertising throughout in app, Relax Rain Latest MOD APK Download removes all commercial content. The popularity of Relax Rain v6.3.1 MOD APK has exploded in recent years due to its numerous benefits over the standard version of the Relax Rain apk. In any case, unlocking mods provides another way for users to customize and enhance their experience on mobile apps.Īlso Read : Touch Macro Pro Mod APK v2.1.2 (Pro) Features of Relax Rain Mod APK And still others may just enjoy playing with upgraded versions of the game objects or graphics. ![]() Others might want extra help in retrieving coins or gems that are hidden in the game. For example, some people like to use Premium features because they feel they get better value for their money. These features can include additional content, new levels, bonus items, and more. These mods can include adding new content, new features and some functions unlocked that provides premium or paid subscription.Ī mod apk is an app that has been modified or “unlocked” to allow access to Premium features. Relax Rain Mod APK v6.3.1 (Premium) : A Relax Rain MOD (mobile application) APK is an unofficial app that provides modifications or “enhancements” to the normal Relax Rain experience on Android devices. How To Install Relax Rain Mod Apk Download.Download Relax Rain MOD APK Latest Version.Download Yours Now! What Is Relax Rain MOD APK This MOD Includes Premium Features Unlocked. Download The Latest Apk Version of Relax Rain MOD, A Lifestyle App For Android Device. Anti-dsDNA antibody isotypes in systemic lupus erythematosus: IgA in addition to IgG anti-dsDNA help to identify glomerulonephritis and active disease. Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. Steady-state generation of mucosal IgA + plasmablasts is not abrogated by B-cell depletion therapy with rituximab. B-cell kinetics in humans: rapid turnover of peripheral blood memory cells. Diversity among memory B cells: origin, consequences, and utility. Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation. ANCA and predicting relapse in systemic vasculitis. IgG1 memory B cells keep the memory of IgE responses. High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes. Non-classical B cell memory of allergic IgE Responses. Lineage tracing of human B cells reveals the in vivo landscape of human antibody class switching. Network properties derived from deep sequencing of human B-cell receptor repertoires delineate B-cell populations. ![]() Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development. Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. Self-reactive VH4-34-expressing IgG B cells recognize commensal bacteria. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype. Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. ![]() The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. Combined influence of B-cell receptor rearrangement and somatic hypermutation on B-cell class-switch fate in health and in chronic lymphocytic leukemia. B-cell selection and the development of autoantibodies. Mechanism and regulation of class switch recombination. IgH chain class switch recombination: mechanism and regulation. Predominant autoantibody production by early human B cell precursors. ![]() Mechanisms of central tolerance for B cells. Instant Notes in Immunology (Bios Scientific, Oxford, 2000). Our comparative analysis of the BCR repertoire in immune-mediated disease reveals a complex B cell architecture, providing a platform for understanding pathological mechanisms and designing treatment strategies. Different immunosuppressive treatments had specific and distinct effects on the repertoire B cells that persisted after treatment with rituximab were predominately isotype-switched and clonally expanded, whereas the inverse was true for B cells that persisted after treatment with mycophenolate mofetil. An increase in clonality in systemic lupus erythematosus and Crohn’s disease that was dominated by the IgA isotype, together with skewed use of the IGHV genes in these and other diseases, suggested a microbial contribution to pathogenesis. Here, we compared the BCR repertoire in systemic lupus erythematosus, anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, Crohn’s disease, Behçet’s disease, eosinophilic granulomatosis with polyangiitis, and immunoglobulin A (IgA) vasculitis by analysing BCR clonality, use of immunoglobulin heavy-chain variable region (IGHV) genes and-in particular-isotype use. Our understanding of the BCR repertoire in the context of immune-mediated diseases is incomplete, and defining this could provide new insights into pathogenesis and therapy. Each B cell expresses a single B cell receptor (BCR) 1, and the diverse range of BCRs expressed by the total B cell population of an individual is termed the ‘BCR repertoire’. B cells are important in the pathogenesis of many, and perhaps all, immune-mediated diseases. ![]() This is a popular and smarter solution in nowadays to perform the app uninstallation. If you want the application removal on the Mac can be faster, easier and more effective, you can consider to take a professional uninstall tool to manage the app removal on your Mac. ![]() More effective option – remove Artstudio Pro with a professional uninstaller Therefore, you also can try to visit the app's website and see whether there is a specific uninstallers for Artstudio Pro. In addition, some publishers might release their own uninstallers, which support users to uninstall their applications on the Mac. After uninstalling the program itself in Applications folder, like the first traditional way, you should go to the user's Library folder either, and then clean all of its application support files, caches and preferences without leaving any file or trace.If you don't have such a specific uninstall process on your Mac, you will have to take another way to perform the app removal.Double-click on its uninstall process, and follow the instruction to remove it.Click to open Artstudio Pro's folder if you have it on your Mac.Click on Go on the top menu, and select Applications.Manual option – remove the app and its files one by one After finishing to clear all of Artstudio Pro's files and traces thoroughly on the Mac, you will just complete the whole removal job on your computer.The same, continue to open Preferences folder in the Library, and delete related preferences of the app or its publisher.Back to the Library window, and click to open Caches this time, delete those caches files of Artstudio Pro.Double click to open Application Support folder in the Library, have a check and delete Artstudio Pro's folder inside.Type "~/library/" in the box, and hit the Return key to access to the user's library folder.Click on Go on the head menu, and click Go to folder.After conducting the above removing steps, you should continue to find and clear everything belonging to Artstudio Pro on the Mac.Right-click on the Trash icon on the Dock, and select Empty Trash to delete the app you just removed.Drag the app's icon to the Trash to remove it,.Quickly, you will see a programs list on the right pane, find and locate Artstudio Pro.Click Finder on the Dock, and then click Applications on the left pane.If you are not sure whether it is running on the Mac at that moment, you can check the Dock, right-click on the app if it appears at there, and select exit Several guides to uninstall Artstudio Pro from Mac Traditional option – remove the application to the Trash Artstudio Pro removal encounters a problem when follow the traditional way to uninstall it, such as removing process has not response or just shut down before finish the removal.Cannot 100% remove all related files of the application.Cannot find and delete all of Artstudio Pro's files and traces on the computer.Not clear what's the right way to remove an application on Mac.Don't know where should start the program removal.Artstudio Pro causes an application conflict issue with other apps on the MacĬommon removing problems you might encounter.The program occupies a lot of space which affect the Mac's performance.Artstudio Pro should be reinstalled on Mac.The application itself encounters a problem which need to remove first.Artstudio Pro gets no use on the computer.General reasons to uninstall Artstudio Pro on Mac Therefore, it will bring some troubles when people need to uninstall Artstudio Pro. However, many people are not clear about these files, and some of these files cannot be found and removed smoothly especially for the basic Mac users. When install Artstudio Pro on the Mac, it will also bring many of its supported files to the Mac, including application support files, preferences, caches etc. ![]() Hard to uninstall Artstudio Pro from Mac? Don't know where the file is or where to start the removal? This post is all about the how-to guides to help you remove this program from Mac. Uninstall Artstudio Pro Guides – How to Remove Artstudio Pro for Mac Now, during a transfer, each packet is signed and optionally encrypted. With the release of macOS 10.12 Sierra, Apple has increased the security of network shares with the more up-to-date SMB2 and SMB3 protocols. If any of the network components do not fully support jumbo frames, it is recommended to use the default MTU 1500 setting to avoid performance degradation. In the Advanced window select the „Hardware“ tab and set „Configure:“ to „Manually“. Click the „Advanced…“ button in the lower right. To set jumbo frames on macOS: access the System Preferences > Network and select the network interface. ![]() You can expect the increased throughput to result in better overall Resolve performance. When jumbo frames are enabled, one can expect an improvement in performance thanks to the fact that every network package will be able to carry more data. If every component of your network infrastructure supports it, set packet size to jumbo frames. Navigate to Preferences > System > Media Storage and turn off Direct I/O on the added mounts. In our 4K 16bit DPX export test on Mac Studio, enabling the Direct I/O feature resulted in exports that were approximately 5X slower. However, enabling Direct I/O will likely decrease performance in virtually any case. This theoretically allows access to the full performance of the drive when using Linux OS. This feature allows DaVinci Resolve to write directly to the drive using the kernel buffers, bypassing the normal storage cache in RAM. These settings can improve real-time playback performance. In DaVinci Resolve, navigate to Preferences > User > Playback Settings and check the “Hide UI overlays” and the “Minimize interface updates during playback”. The maximum and the default setting for this preference is 75 percent of your system’s RAM. To set a memory limit navigate to Preferences > Memory and GPU > System. Please keep in mind that the amount of RAM required for optimum performance depends on your workflow. It is recommended that memory allocation for DaVinci Resolve is increased to 32 GB or above. This is the lowest possible amount of RAM to get Resolve up and running. If you require a general overview of achieving better playback performance in DaVinci Resolve, head to our blog: DaVinci Resolve: 5 ways to achieve better playback performance DaVinci Resolve Settings Set Memory Usage LimitĭaVinci Resolve 18 requires at least 8 GB of system memory to run on macOS and 16 GB when using Fusion. This blog will show you how to optimise your DaVinci Resolve on Mac Studio setup for performance over an SMB connection. These include the network and client settings, as well as the application settings. ![]() To meet these requirements, every component of the setup must be optimised. The need to work with the highest possible video bitrate, often with raw codecs, makes the color grading process one of the most performance-demanding in the post-production workflow. |